Treatments · 97 clinics in 9 countries · checked 21 Oct 2026

Hormone therapy: evidence, regulation and where it is offered

Hormone therapy replaces or adds hormones such as oestrogen, progesterone or testosterone, and is a prescription treatment. Our evidence label for it is Depends on use. Established for some medical conditions, unproven as a longevity treatment. 97 clinics we list offer it, in the United States, the United Kingdom, Germany, Spain, Indonesia, Thailand, Australia, the United Arab Emirates and Mexico.

DEPENDS ON USE

What the evidence says

Prescription status: a prescription-only treatment. We show no prices for it where the rules forbid advertising prescription medicines.

Hormone therapy is an established treatment for some conditions. In the UK, the National Institute for Health and Care Excellence (NICE) recommends offering hormone replacement therapy (HRT) for hot flushes and night sweats around the menopause, after talking through the benefits and risks (NICE guideline NG23). In the US, menopause hormone products are approved for moderate to severe hot flushes, vaginal dryness and preventing bone loss (FDA, February 2026).

For men, the Endocrine Society says low testosterone should be diagnosed only when a man has symptoms and clearly and consistently low levels. It recommends against routinely prescribing testosterone to all men aged 65 or over with low levels (Endocrine Society, 2018).

None of these guidelines or approvals is for slowing ageing.

Regulators and prescription status

United States. The US Food and Drug Administration (FDA) approves testosterone only for men with low testosterone linked to a medical condition. In February 2025 it kept a limit on its use for low testosterone due to ageing, and added warnings about raised blood pressure (FDA, 2025). In February 2026 it removed statements on heart disease, breast cancer and probable dementia from the boxed warning of six menopause hormone products.

Depends on use means: Established for some medical conditions, unproven as a longevity treatment.

What regulators say

CountryNoteSource
United StatesTestosterone products are not approved for low testosterone caused by ageing alone; the FDA kept this limitation in its 2025 labelling update.FDA, 28 February 2025
United KingdomNo regulator statement recorded yet.
GermanyNo regulator statement recorded yet.
SpainNo regulator statement recorded yet.
IndonesiaNo regulator statement recorded yet.
ThailandNo regulator statement recorded yet.
AustraliaNo regulator statement recorded yet.
United Arab EmiratesNo regulator statement recorded yet.
MexicoNo regulator statement recorded yet.

Where it is offered

Bali1 clinic

Published prices

Prices are not shown in the United Kingdom, Germany, Spain, Indonesia, Thailand, Australia, the United Arab Emirates and Mexico: it is a prescription-only treatment there.

No price that may be shown is published by the clinics we list.

Safety and questions to ask

NICE says HRT with oestrogen alone makes little or no difference to the risk of breast cancer. HRT that combines oestrogen with a progestogen can raise the risk, depending on how long it is taken, and the risk falls after it stops. HRT tablets raise the risk of blood clots; patches and gels at standard doses do not. Testosterone can raise blood pressure.

  1. Will a doctor who can prescribe see me and test my hormone levels first?
  2. What is the treatment for, and how will we know if it works?
  3. Is the product a licensed medicine, or made up by a pharmacy?
  4. What are the risks for me, and how often will I have follow-up tests?
  5. Will my own doctor be told?

Sources